Whang-Peng J, Lee E C, Forni G, Green I
J Natl Cancer Inst. 1976 Oct;57(4):897-905. doi: 10.1093/jnci/57.4.897.
Chromosomes of normal guinea pig (strain 2) cells and of cell lines dervied from a spontaneously arising leukemia were analyzed in detail. All cell lines studied, LG-L2C, GH-L2-C, BZ-LC, and EN-L2C, contained one M1 marker and two X chromosomes, in addition to other chromosome abnormalities specific for each cell line. The presence of the M1 marker and the two X chromosomes confirmed that all of these leukemic cell lines are derived from one ancestral line. Comparison of the chromosome markers and immunologic characteristics of these lines revealed that possibly the gene involved in the determination of C3 receptor sites is located on the terminal portion of the long arm of chromosome No. 2, but no other correlations could be made.
对正常豚鼠（2号品系）细胞以及源自自发产生的白血病的细胞系的染色体进行了详细分析。所研究的所有细胞系，即LG-L2C、GH-L2-C、BZ-LC和EN-L2C，除了各细胞系特有的其他染色体异常外，均含有一个M1标记和两条X染色体。M1标记和两条X染色体的存在证实所有这些白血病细胞系均源自一个祖系。对这些细胞系的染色体标记和免疫特征进行比较后发现，参与C3受体位点决定的基因可能位于2号染色体长臂的末端部分，但未发现其他相关性。
