Ivey M F, Baluch W, Mueller W
Am J Hosp Pharm. 1979 Jan;36(1):57-9.
The administrative process of adding a 5.5% crystalline amino acid solution to the formulary of two affiliated hospitals and the results of the addition are discussed. A formulary change was sought after it was found that many patients on parenteral nutrient therapy were receiving more amino acids than they needed. Nearly all patients on parenteral nutrient therapy were receiving 8.5% crystalline amino acid solution. The approach to achieving the pharmacy and therapeutics committee's approval of the formulary change included documenting amino acid needs from the literature, securing a multidisciplinary base of support and providing economic impact information. A standard TPN order form for physicians, education through the pharmacy newsletter, and presentations at surgery and medical conferences and grand rounds were implemented to assure that the change was effective. During the 12 months following approval of the formulary addition, 66% of the more than 20,000 total parenteral nutrient solutions were prepared using 5.5% amino acid solutions. This resulted in an annual savings of $41,028
讨论了将5.5%结晶氨基酸溶液添加到两家附属医院处方集的管理过程及添加结果。在发现许多接受肠外营养治疗的患者摄入的氨基酸超过其所需量后，寻求对处方集进行更改。几乎所有接受肠外营养治疗的患者都在使用8.5%结晶氨基酸溶液。获得药学与治疗学委员会对处方集更改批准的方法包括记录文献中的氨基酸需求、获得多学科支持基础并提供经济影响信息。实施了面向医生的标准全胃肠外营养（TPN）订单表格、通过药房通讯进行教育以及在外科和医学会议及大查房上进行汇报，以确保更改有效。在处方集添加获批后的12个月内，超过20000份肠外营养溶液中有66%使用5.5%氨基酸溶液配制。这带来了每年41028美元的节省。
