[Anastomosis of the vas deferens employing concentrated fibrinogen: an experimental study in rabbits (authors transl)].

Bilateral vaso-vasostomy was carried out in 30 rabbits using highly concentrated fibrinogen in combination with thrombin and clotting Factor XIII for tissue adhesion. The patency of the anastomoses was confirmed radiologically and by the injection of a dye, as well as histologically in paraffin-embedded and Goldner-stained serial sections. The overall patency amounted to 58% in animals investigated 4--6 weeks postoperatively (i.e. 17 out of 30 anastomoses). Stenosis of the junction was observed in all patent anastomoses investigated. The results of vaso-vasostomy employing a biological tissue adhesive were markedly superior to those with cyanoacylate.