Sarosi G A, Serstock D S
Am Rev Respir Dis. 1976 Dec;114(6):1179-83. doi: 10.1164/arrd.1976.114.6.1179.
We recently diagnosed and treated a 45-year-old white male horticulturist with acute progressive blastomycosis. Epidemiologic studies revealed that the patient used a load of pigeon manure as fertilizer approximately 6 weeks before becoming ill. He used the pigeon manure only once, resealed the remainder, and stored it in his hothouse. Samples of the pigeon guano were digested with 10 per cent KOH, and the characteristic yeast forms of Blastomyces dermatitidis were seen in large numbers. The fungus was cultured from another sample of the same material. This is the first time that the pathogenic fungus B. dermatitidis has been isolated from the environment in association with a human case.
我们最近诊断并治疗了一名45岁的白人男性园艺师,他患有急性进行性芽生菌病。流行病学研究显示,该患者在发病前约6周使用了一批鸽粪作为肥料。他只使用了一次鸽粪,将剩余的重新密封,并储存在他的温室中。将鸽粪样本用10%氢氧化钾消化后,发现大量皮炎芽生菌的特征性酵母形态。从同一材料的另一个样本中培养出了该真菌。这是首次从与人类病例相关的环境中分离出致病性真菌皮炎芽生菌。