A new antibiotic nortriterpene quinone methide from Maytenus catingarum.
作者信息
Alvarenga N L, Velázquez C A, Gómez R, Canela N J, Bazzocchi I L, Ferro E A
机构信息
Departamento de Fitoquímica, Dirección de Investigación, Facultad de Ciencias Químicas de la Universidad Nacional de Asunción, P.O. Box 1.055 Asunción, Paraguay.
出版信息
J Nat Prod. 1999 May;62(5):750-1. doi: 10.1021/np980359p.
PMID:10346960
Abstract
15alpha-Hydroxy-21-keto-pristimerine (1), a new nortriterpene quinone methide was isolated from the root bark of Maytenus catingarum along with other well-known related compounds, including pristimerine (2), tingenone, and 20alpha-hydroxy-tingenone. The structure of 1 was determined by means of 1H and 13C NMR spectroscopy, including homonuclear and heteronuclear correlations. Compound 1 showed antibiotic activity against Gram-positive bacteria.
摘要
相似文献
1
A new antibiotic nortriterpene quinone methide from Maytenus catingarum.
J Nat Prod. 1999 May;62(5):750-1. doi: 10.1021/np980359p.
2
The isolation, purification and biological activity of a novel antibacterial compound produced by Pseudomonas stutzeri.
FEMS Microbiol Lett. 2008 Feb;279(2):243-50. doi: 10.1111/j.1574-6968.2007.01036.x. Epub 2007 Dec 17.
3
Synthesis and antibacterial evaluation of 1beta-methyl-2-[5-(1-methoxyimino-2-substituted sulfonamide ethyl)pyrrolidin-3-ylthio]carbapenems and their related compounds.
Eur J Med Chem. 2007 Mar;42(3):358-64. doi: 10.1016/j.ejmech.2006.10.006. Epub 2006 Dec 6.
4
Flavones and sesquiterpene lactones from Achillea atrata subsp. multifida: antimicrobial activity.
J Nat Prod. 1999 Jun;62(6):909-11. doi: 10.1021/np980536m.
5
A furanoid labdane diterpene from Potamogeton nodosus.
J Nat Prod. 1998 Jan;61(1):156-7. doi: 10.1021/np9702244.
6
Isolation, characterization and antimicrobial activity of coumarin derivatives from Cyperus incompletus.
Boll Soc Ital Biol Sper. 1992 Jul;68(7):453-61.
7
1-Hydroxy-1-norresistomycin, a new cytotoxic compound from a marine actinomycete, Streptomyces chibaensis AUBN1/7.
J Antibiot (Tokyo). 2005 Aug;58(8):526-9. doi: 10.1038/ja.2005.72.
8
Albidopyrone, a new alpha-pyrone-containing metabolite from marine-derived Streptomyces sp. NTK 227.
J Antibiot (Tokyo). 2009 Feb;62(2):75-9. doi: 10.1038/ja.2008.15. Epub 2009 Jan 9.
9
A new ene-triyne antibiotic from the fungus Baeospora myosura.
J Nat Prod. 2004 Nov;67(11):1900-2. doi: 10.1021/np0497853.
10
Synthesis of some new 2,5-disubstituted 1,3,4-thiadiazoles containing isomeric pyridyl as potent antimicrobial agents.
Pol J Pharmacol. 2003 Nov-Dec;55(6):1111-7.
引用本文的文献
1
A Review on Phytochemicals of the Genus and Their Bioactive Studies.
Molecules. 2021 Jul 28;26(15):4563. doi: 10.3390/molecules26154563.
2
Evaluation of antioxidant capacity and synergistic associations of quinonemethide triterpenes and phenolic substances from Maytenus ilicifolia (Celastraceae).
Molecules. 2010 Oct 11;15(10):6956-73. doi: 10.3390/molecules15106956.
Zotero 插件