Cohen S R, Landing B H, Isaacs H, King K K, Hanson V
Ann Otol Rhinol Laryngol Suppl. 1978 Sep-Oct;87(5 Pt 2 Suppl 52):11-4. doi: 10.1177/00034894780870s503.
Solitary plasmacytoma rarely involves the larynx and trachea. This tumor caused severe laryngeal and tracheal obstruction in an adolescent female with systemic lupus erythematosus of nine years' duration. Her systemic disease had been in remission at the time she developed symptoms of laryngeal and tracheal obstruction by plasmacytoma invasion. A complete survey failed to reveal any other focus of tumor. Because steroid therapy failed to clear the plasma cell infiltrate, she was treated with irradiation after the tumor was surgically debulked endoscopically. Postirradiation biopsy showed no evidence of tumor, but the patient continued to experience moderate airway obstruction from fibrosis in the irradiated trachea. The patient has been followed, and is free of disease nine years after establishing the diagnosis.
孤立性浆细胞瘤很少累及喉和气管。该肿瘤导致一名病程九年的青少年女性系统性红斑狼疮患者出现严重的喉和气管梗阻。在她因浆细胞瘤侵犯出现喉和气管梗阻症状时，其全身性疾病处于缓解期。全面检查未发现任何其他肿瘤病灶。由于类固醇治疗未能清除浆细胞浸润，在通过内镜手术切除大部分肿瘤后，她接受了放射治疗。放疗后活检未发现肿瘤证据，但患者仍因放疗后气管纤维化持续存在中度气道梗阻。该患者一直在接受随访，确诊九年后未再出现疾病。
