Uppal H S, Harrison P
Department of Otolaryngology, Head and Neck Surgery, Russells Hall Hospital, Dudley, UK.
J Laryngol Otol. 2001 Sep;115(9):745-6. doi: 10.1258/0022215011908829.
A rare case of upper airway obstruction due to an extramedullary plasmacytoma of the larynx in a patient with long-standing IgD myeloma is presented. Reports of patients with extramedullary plasmacytomas eventually developing multiple myeloma are common, however, the converse appears to be an extremely rare event. Attention is drawn to the problem of acquiring adequate tissue for diagnostic purposes as well as the use of immunohistochemical staining techniques. The patient required an urgent tracheostomy and was treated with radiotherapy.
本文报告了一例长期患有IgD骨髓瘤的患者因喉髓外浆细胞瘤导致上呼吸道梗阻的罕见病例。髓外浆细胞瘤患者最终发展为多发性骨髓瘤的报道很常见,然而,反之情况似乎极为罕见。文中提请注意获取足够组织用于诊断目的的问题以及免疫组织化学染色技术的应用。该患者需要紧急气管切开术并接受放射治疗。