Solomon S, Kurian N, Ramadas P, Rao P S
Branch of Surgery, Schieffelin Leprosy Research and Training Center, District, Tamil Nadu, India.
Int J Lepr Other Mycobact Dis. 1998 Dec;66(4):451-6.
The incidence rates of sensory and motor impairments during and after multidrug therapy (MDT) are reported for a prospective cohort of patients who had no nerve damage at registration (N = 1621). Sensory and motor loss increased with age and both were high among multibacillary patients as compared with paucibacillary patients. The lateral popliteal (common peroneal) and posterior tibial nerves seem to be most affected for sensory loss; whereas the posterior tibial and ulnar nerves are mainly responsible for motor loss. No significant difference by gender was found. Implications for prevention of disability (POD) activities are discussed and suitable recommendations made.
报告了多药疗法（MDT）期间及之后感觉和运动障碍的发病率，该报告基于登记时无神经损伤的前瞻性队列患者（N = 1621）。感觉和运动功能丧失随年龄增长而增加，与少菌型患者相比，多菌型患者中两者的发生率都很高。感觉丧失似乎以腓总神经和胫后神经受影响最为严重；而运动功能丧失主要由胫后神经和尺神经引起。未发现性别之间存在显著差异。讨论了对预防残疾活动的影响并提出了适当建议。
