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韦格纳肉芽肿病致一名青春期女孩喉及气管支气管梗阻

Wegener's granulomatosis causing laryngeal and tracheobronchial obstruction in an adolescent girl.

作者信息

Cohen S R, Landing B H, King B K, Isaacs H

出版信息

Ann Otol Rhinol Laryngol Suppl. 1978 Sep-Oct;87(5 Pt 2 Suppl 52):15-9. doi: 10.1177/00034894780870s504.

DOI:10.1177/00034894780870s504
PMID:103476
Abstract

A 12-year-old girl presenting with a painful neck mass and ulcerated gingival lesions was found to have Wegener's granulomatosis involving the gingivae, paranasal sinuses, ears, mastoids, larynx, trachea, bronchial tree, lungs, kidneys and joints. The initial illness and two subsequent exacerbations were treated with intravenous and oral cyclophosphamide and prednisone. Secondary infections have been managed with establishment of good drainage and use of appropriate antibiotics. The patient is well with a normal sedimentation rate 4 1/2 years after the onset of her disease.

摘要

一名12岁女孩因颈部疼痛性肿块和牙龈溃疡病变就诊,被发现患有韦格纳肉芽肿,累及牙龈、鼻窦、耳朵、乳突、喉、气管、支气管树、肺、肾和关节。最初的疾病以及随后的两次病情加重均采用静脉和口服环磷酰胺及泼尼松进行治疗。通过建立良好的引流和使用适当的抗生素来处理继发感染。该患者在疾病发作4年半后情况良好,血沉正常。

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Wegener's granulomatosis causing laryngeal and tracheobronchial obstruction in an adolescent girl.韦格纳肉芽肿病致一名青春期女孩喉及气管支气管梗阻
Ann Otol Rhinol Laryngol Suppl. 1978 Sep-Oct;87(5 Pt 2 Suppl 52):15-9. doi: 10.1177/00034894780870s504.
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Chest CT findings in pediatric Wegener's granulomatosis.儿童韦格纳肉芽肿的胸部CT表现。
Pediatr Radiol. 2007 Jan;37(1):57-62. doi: 10.1007/s00247-006-0341-9. Epub 2006 Oct 28.
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Wegener's granulomatosis in childhood. Review of the literature and case report.儿童韦格纳肉芽肿病。文献综述及病例报告
Pediatr Radiol. 1984;14(5):267-71. doi: 10.1007/BF01601872.
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Wegener's granulomatosis: isolated involvement of the trachea and larynx.韦格纳肉芽肿病:气管和喉部的孤立性受累。
Ann Rheum Dis. 1987 Aug;46(8):628-31. doi: 10.1136/ard.46.8.628.
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Hilar and mediastinal lymphadenopathy in the limited form of Wegener's granulomatosis.局限性韦格纳肉芽肿病中的肺门及纵隔淋巴结肿大
Thorax. 1991 Mar;46(3):219-20. doi: 10.1136/thx.46.3.219.