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[一例成人急性小脑炎后周围性面神经麻痹病例,伴有高滴度抗水痘-带状疱疹病毒抗体]

[An adult case of peripheral facial nerve palsy following acute cerebellitis associated with high antibody titers against varicella-zoster virus].

作者信息

Ogata K, Yamada T, Hara H, Taniwaki T, Kira J

机构信息

Department of Neurology, Faculty of Medicine, Kyushu University, Fukuoka.

出版信息

Rinsho Shinkeigaku. 1998 Dec;38(12):1070-2.

PMID:10349352
Abstract

Here we report a case of acute cerebellitis, in which the patient developed right peripheral facial palsy during the recovery phase of cerebellar ataxia. A 67-year-old man developed truncal and limb ataxia following a fever, general fatigue and anorexia. He was diagnosed to have acute cerebellitis. While the ataxia symptoms were improving without any treatment, right peripheral facial nerve palsy developed and an MRI revealed an enhancement of the right facial nerve proximal to the geniculate ganglion. After treatment with acyclovir and corticosteroids, his facial nerve palsy and ataxia both gradually improved. There has been no previous report of an adult case who developed peripheral facial nerve palsy during the recovery phase of acute cerebellitis. This case indicates that a wide spectrum of neurological complications may develop in association with a varicella-zoster virus infection.

摘要

在此,我们报告一例急性小脑炎病例,该患者在小脑共济失调的恢复期出现了右侧周围性面瘫。一名67岁男性在发热、全身乏力和厌食后出现躯干和肢体共济失调。他被诊断为急性小脑炎。在未进行任何治疗的情况下,共济失调症状正在改善时,右侧周围性面神经麻痹出现,磁共振成像(MRI)显示膝状神经节近端的右侧面神经强化。在接受阿昔洛韦和皮质类固醇治疗后,他的面神经麻痹和共济失调均逐渐改善。此前尚无关于成人在急性小脑炎恢复期出现周围性面神经麻痹的病例报告。该病例表明,水痘-带状疱疹病毒感染可能会引发广泛的神经系统并发症。

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[An adult case of peripheral facial nerve palsy following acute cerebellitis associated with high antibody titers against varicella-zoster virus].[一例成人急性小脑炎后周围性面神经麻痹病例,伴有高滴度抗水痘-带状疱疹病毒抗体]
Rinsho Shinkeigaku. 1998 Dec;38(12):1070-2.
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High prevalence of varicella-zoster virus reactivation in herpes simplex virus-seronegative patients with acute peripheral facial palsy.单纯疱疹病毒血清学阴性的急性周围性面神经麻痹患者中水痘-带状疱疹病毒再激活的高发生率。
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An elderly case of acute cerebellitis after alleged vaccination.疑似接种疫苗后出现老年急性小脑炎病例。
J Mov Disord. 2012 May;5(1):21-3. doi: 10.14802/jmd.12006. Epub 2012 May 30.
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A case of ramsay hunt syndrome complicated by cerebellitis.一例拉姆齐·亨特综合征并发小脑炎。
J Clin Neurol. 2006 Sep;2(3):198-201. doi: 10.3988/jcn.2006.2.3.198. Epub 2006 Sep 20.
3
Hemicerebellitis mimicking a tumour on MRI.磁共振成像(MRI)上表现类似肿瘤的半侧小脑炎。
Childs Nerv Syst. 2003 Feb;19(2):122-5. doi: 10.1007/s00381-002-0709-6. Epub 2003 Jan 29.