Mang W L, Bonkowsky V M
HNO. 1987 Jul;35(7):310-3.
The possible association of some viral infections with the onset of Bell's palsy was examined in a study of 29 patients. The results were compared with a sex- and age-matched control group. The number of probable recent viral infections, as judged by a fourfold increase in antibody titers or the presence of specific IgM antibodies, differed statistically from that found in the control group. In seven patients with Bell's palsy the enzyme-linked-immunosorbent assay (ELISA) indicated an acute viral infection (herpes simplex 4; varicella zoster 2; cytomegalovirus 1). All these infections were due to viruses belonging to the herpesvirus group. Clinical evidence of herpesvirus infection was found in three cases (Herpetic eruption). The aetiological relationship between the virological findings and Bell's palsy is discussed. Reactivated herpes simplex virus and transient demyelination of the facial nerve could be one cause of an idiopathic facial palsy.
在一项针对29名患者的研究中,对某些病毒感染与贝尔麻痹发病之间可能存在的关联进行了调查。将结果与性别和年龄匹配的对照组进行了比较。根据抗体滴度四倍增加或特异性IgM抗体的存在判断,近期可能发生的病毒感染数量与对照组相比有统计学差异。在7例贝尔麻痹患者中,酶联免疫吸附测定(ELISA)显示存在急性病毒感染(单纯疱疹病毒4例;水痘带状疱疹病毒2例;巨细胞病毒1例)。所有这些感染均由疱疹病毒组的病毒引起。在3例患者中发现了疱疹病毒感染的临床证据(疱疹性皮疹)。讨论了病毒学检查结果与贝尔麻痹之间的病因学关系。单纯疱疹病毒再激活和面神经短暂性脱髓鞘可能是特发性面神经麻痹的一个原因。