Wendt T M, Cornell J H, Kaplan A M
Appl Environ Microbiol. 1978 Nov;36(5):693-9. doi: 10.1128/aem.36.5.693-699.1978.
The fate of glycerol trinitrate when exposed to microbial attack has been investigated. Contrary to some earlier reports, this compound was readily biodegraded by employing batch or continuous techniques under a variety of cultural conditions. Breakdown of glycerol trinitrate took place stepwise via the dinitrate and mononitrate isomers, with each succeeding step proceeding at a slower rate. After a residence time of 8 to 15 h, none of the glycerol nitrates could be detected in the effluent from a continuous-culture apparatus (chemostat) supplied with an influent containing 30 mg of glycerol trinitrate per liter.
甘油三硝酸酯在遭受微生物攻击时的命运已得到研究。与一些早期报告相反,在各种培养条件下,采用分批或连续技术时,该化合物很容易被生物降解。甘油三硝酸酯通过二硝酸酯和单硝酸酯异构体逐步分解,每一步后续反应的速率都较慢。在停留时间为8至15小时后,在配备有每升含30毫克甘油三硝酸酯进水的连续培养装置(恒化器)的流出物中,检测不到任何甘油硝酸盐。