Kunz G, Englisch H J, Wenzel J
J Hirnforsch. 1976;17(4):351-63.
The distribution of the dendritic spines in the CA1 hippocampal region of adult rats was investigated by means of lightmicroscopical and statistical methods. The rats received daily equal amounts of aethanol for a period of 52 days. The average number of spines for a part of 50 mum along the apical main dendrite raised from 35 to 36.9 spines. The average spines-density for a part of 1 mum length on the apical dendritic branches raised from 0.71 to 0.94 spines. In a similar way the average spines-density on the basal dendritic branches raised from 0.65 to 0.94 spines. According to our results received after a period of aethanol application the total number of dendritic spines of one rat CA1 hippocampal pyramidal neuron was calculated with 4177 visible spines. The value was compared with the normal value of 3029 dendritic spines. The results were discussed by the aid of additional light- and electronmicroscopical findings.
采用光学显微镜和统计学方法研究成年大鼠海马CA1区树突棘的分布。大鼠连续52天每天给予等量乙醇。沿顶端主树突50μm部分的棘突平均数量从35个增加到36.9个。顶端树突分支上1μm长度部分的平均棘突密度从0.71个增加到0.94个。同样，基底树突分支上的平均棘突密度从0.65个增加到0.94个。根据乙醇处理一段时间后得到的结果，计算出一只大鼠CA1海马锥体细胞的树突棘总数为4177个可见棘突。该值与正常的3029个树突棘值进行了比较。借助额外的光学和电子显微镜观察结果对这些结果进行了讨论。
