Banegas Banegas J R, Rodríguez-Artalejo F, de la Cruz Troca J J, de Andrés Manzano B, del Rey Calero J
Departamento de Medicina Preventiva, Facultad de Medicina, Universidad Autónoma de Madrid.
Med Clin (Barc). 1999 Apr 17;112(13):489-94.
Given the high figures of cardiovascular disease and hypertension in Spain, and the continuity of cardiovascular and total mortality risks at any level of blood pressure, mortality related to hypertension and blood pressure is estimated.
Blood pressure distribution from a representative sample of the 35 to 64 years old Spanish population and the relative risks for death coming from valid and reasonably generalizable international studies (MRFIT, Framingham and Chicago Project) were used. The proportions and absolute numbers of cardiovascular and total deaths related to blood pressure and hypertension (categories of the US Joint National Committee VI [JNC VI]) have been calculated in middle-aged men and women.
As many as 42% of the coronary deaths, 46.4% of the stroke deaths and 25.5% of the total deaths are related to hypertension (> or = 140/90 mmHg), most of them in stages 1 and 2. It follows high-normal plus normal blood pressure group (8.3, 10.2 and 6.2% of these deaths, respectively). All together, 17,266 total deaths and 4,502 cardiovascular deaths related to blood pressure took place annually, three-quarters of them in males. Over the last ones, 65.5% are coronary and 34.5% cerebrovascular, prevailing the first ones in both sexes. Eight out of 10 deaths, cardiovascular or total, related to blood pressure are concentrated in the hypertension categories, and two out of 10 in the high-normal or normal blood pressure groups.
One out of 3 total deaths and one out of 2 cardiovascular deaths are related to blood pressure. One out of 4 total deaths and one out of 2.5 cardiovascular deaths are related to hypertension. A substantial part of these deaths come from stages 1 and 2 hypertension and from high-normal and normal blood pressure group.
鉴于西班牙心血管疾病和高血压的高发率,以及血压处于任何水平时心血管疾病和全因死亡风险的持续性,对与高血压和血压相关的死亡率进行了估算。
采用了来自35至64岁西班牙人群代表性样本的血压分布数据,以及来自有效且具有合理普遍性的国际研究(多重危险因素干预试验、弗雷明汉心脏研究和芝加哥项目)的死亡相对风险数据。计算了中年男性和女性中与血压和高血压(美国国家联合委员会第六版 [JNC VI] 分类)相关的心血管死亡和全因死亡的比例及绝对数量。
多达42%的冠心病死亡、46.4%的中风死亡和25.5%的全因死亡与高血压(收缩压≥140 mmHg和/或舒张压≥90 mmHg)相关,其中大部分处于1期和2期。其次是血压略高于正常范围加上正常血压组(分别占这些死亡的8.3%、10.2%和6.2%)。每年共有17266例全因死亡和4502例与血压相关的心血管死亡,其中四分之三发生在男性中。在后者中,65.5%为冠心病死亡,34.5%为脑血管死亡,并在两性中以冠心病死亡为主。与血压相关的心血管或全因死亡中,十分之八集中在高血压类别,十分之二集中在血压略高于正常范围或正常血压组。
三分之一的全因死亡和二分之一的心血管死亡与血压相关。四分之一的全因死亡和二点五分之一的心血管死亡与高血压相关。这些死亡中的很大一部分来自1期和2期高血压以及血压略高于正常范围和正常血压组。