Effects of Fructus schizandrae on cycloheximide-induced amnesia in rats.

作者信息

Hsieh M T, Tsai M L, Peng W H, Wu C R

机构信息

Institute of Chinese Pharmaceutical Sciences, China Medical College, Taichung, Taiwan, R.O.C.

出版信息

Phytother Res. 1999 May;13(3):256-7. doi: 10.1002/(SICI)1099-1573(199905)13:3<256::AID-PTR435>3.0.CO;2-H.

The effects of Fructus Schisandrae (Schizandra Chinensis, (FS) on cycloheximide (CXM)-induced amnesia by using a passive avoidance task were studied in rats. FS at 0.25 and 0.75 g/kg administered for 1 week significantly prolonged the CXM-shortened step-through latency (STL). Of the fractions (n-hexane, chloroform and water), only the water fraction at 25 mg/kg administered for 1 week prolonged the CXM-shortened STL. These results suggest that the water fraction is the main active fraction of FS.