Fuentes L J, Santiago E
Departamento de Psicología Experimental y Psicobiología, Universidad de Almería, Spain.
Neuropsychology. 1999 Apr;13(2):259-70. doi: 10.1037//0894-4105.13.2.259.
Two experiments assessed inhibitory mechanisms associated with the posterior and anterior attention networks in schizophrenia. Experiment 1 assessed the inhibition of return effect of the posterior network. Both healthy adults and schizophrenic adults showed inhibition of return, suggesting that this inhibitory mechanism of visual orienting is preserved in schizophrenia. Experiment 2 assessed semantic inhibition, which supposedly taps the anterior network, in a lexical-decision task. Healthy adults showed semantic inhibition effects in both visual fields. Schizophrenic adults showed semantic inhibition effects when targets were presented to the left visual field, involving the right hemisphere. However, semantic facilitation rather than inhibition was observed when targets were presented to the right visual field, involving the left hemisphere. These results reflect left hemisphere dysfunction associated with deficits in attentional control in schizophrenia.
两项实验评估了精神分裂症患者与后部和前部注意网络相关的抑制机制。实验1评估了后部网络的返回抑制效应。健康成年人和精神分裂症成年患者均表现出返回抑制，这表明视觉定向的这种抑制机制在精神分裂症中得以保留。实验2在词汇判断任务中评估了语义抑制，该抑制被认为利用了前部网络。健康成年人在两个视野中均表现出语义抑制效应。当目标呈现给涉及右半球的左视野时，精神分裂症成年患者表现出语义抑制效应。然而，当目标呈现给涉及左半球的右视野时，观察到的是语义促进而非抑制。这些结果反映了与精神分裂症患者注意力控制缺陷相关的左半球功能障碍。
