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急性早幼粒细胞白血病中的外周动脉闭塞

Peripheral arterial occlusion in acute promyelocytic leukemia.

作者信息

DiGiovanni R J, Crilley P, Kerstein M D

机构信息

Allegheny University Hospitals/Allegheny University of the Health Sciences, Medical College of Pennsylvania/Hahnemann University, Philadelphia 19102-1192, USA.

出版信息

Cardiovasc Surg. 1999 Mar;7(2):258-60. doi: 10.1016/s0967-2109(98)00043-x.

DOI:10.1016/s0967-2109(98)00043-x
PMID:10353683
Abstract

A 16-year-old Caucasian teenager developed fatigue, abdominal pain, pneumonia, and subsequently acute vascular occlusion of the left superficial femoral artery. Vascular assessment and heparin therapy lead to bone marrow aspiration and a diagnosis of acute promyelocytic leukemia. Treatment with chemotherapy prevented loss of limb and avoided further vascular surgery. Young patients with acute vascular occlusion require an in-depth assessment including attention to hematological disorders. Clots obtained on thromboembolectomy should be sent for pathological assessment and not discarded, especially in an unusual-age patient for arterial embolus.

摘要

一名16岁的白种青少年出现疲劳、腹痛、肺炎,随后左侧股浅动脉发生急性血管闭塞。血管评估和肝素治疗导致进行骨髓穿刺,并诊断为急性早幼粒细胞白血病。化疗治疗避免了肢体丧失,也避免了进一步的血管手术。急性血管闭塞的年轻患者需要进行深入评估,包括关注血液系统疾病。血栓切除术取出的血栓应送去做病理评估,而不应丢弃,特别是对于动脉栓塞的非典型年龄患者。

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Severe Lower Limb Ischemia by Massive Arterial Thrombosis Revealing an Acute Myeloid Leukemia Needing for Leg Amputation: Clinical and Emotional Aspects Related to the Communication with the Patient and His Family.巨大动脉血栓形成导致严重下肢缺血,进而揭示出一例需要截肢的急性髓系白血病:与患者及其家属沟通相关的临床及情感方面问题
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