D'Angelo Paolo, Taormina Calogero, Mosa Clara, Di Marco Floriana, Valentino Fabrizio, Trizzino Angela, Guadagna Paola, Talarico Francesco
Pediatric Hematology and Oncology Department.
Vascular Surgery Department, A.R.N.A.S Civico, Di Cristina e Benfratelli Hospitals , Palermo, Italy.
Pediatr Rep. 2016 Dec 9;8(4):6885. doi: 10.4081/pr.2016.6885. eCollection 2016 Nov 17.
Large vessel thrombosis is a very rare clinical presentation of acute leukemia, generally associated with coagulopathy, usually characteristic of acute promyelocytic leukemia. A 13- year-old boy with a previously undiagnosed acute myeloid leukemia was referred to our hospital with acute ischemia of the right lower limb due to occlusion of the right external iliac artery, treated with emergency double surgical thromboembolectomy and chemotherapy. The thrombotic complication resulted in leg amputation. Now the boy is well in complete remission, with a good social integration and quality of life, 30 months after completing treatment. The report highlights the crucial role of early diagnosis and subsequent chemotherapy in avoiding amputation. We particularly focused critical and emotional aspects related to the communication about the leg amputation with the patient and his family.
大血管血栓形成是急性白血病一种非常罕见的临床表现，通常与凝血功能障碍有关，这通常是急性早幼粒细胞白血病的特征。一名13岁男孩此前未被诊断出患有急性髓系白血病，因右髂外动脉闭塞导致右下肢急性缺血被转诊至我院，接受了急诊双手术取栓和化疗。血栓形成并发症导致腿部截肢。现在，该男孩在完成治疗30个月后处于完全缓解状态，社会融入良好，生活质量良好。该报告强调了早期诊断和后续化疗在避免截肢方面的关键作用。我们特别关注了与患者及其家属就腿部截肢进行沟通时的关键和情感方面。
