Jori A, Colturani F, Dolfini E, Rutczynski M
Neuroendocrinology. 1976;21(3):262-6. doi: 10.1159/000122531.
The metabolism of striatum dopamine (DA) was studied in mice during proestrus, estrus and diestrus. The following results have been obtained: (1) the concentration of DA is higher in diestrus than in proestrus and estrus; (2) the concentration of its metabolite, homovanillic acid (HVA), is maximum in the estrus phase; (3) the DA turnover, evaluated by measuring the DA disappearance after blocking synthesis with methyltyrosine, is faster in estrus than in the other phases. These results have been discussed in view of the possible role of dopaminergic mechanisms in the control of gonadotropin secretion.
在小鼠的动情前期、发情期和动情间期研究了纹状体多巴胺（DA）的代谢。得到了以下结果：（1）动情间期的DA浓度高于动情前期和发情期；（2）其代谢产物高香草酸（HVA）的浓度在发情期最高；（3）通过用甲基酪氨酸阻断合成后测量DA消失来评估的DA周转率，在发情期比其他阶段更快。鉴于多巴胺能机制在促性腺激素分泌控制中的可能作用，对这些结果进行了讨论。
