Boltshauser S, Herzog D
Ostschweizer Kinderspital, St. Gallen.
Schweiz Med Wochenschr. 1999 Apr 17;129(15):579-84.
The prevalence of Helicobacter pylori infection in asymptomatic Swiss children is not known. The aim of this study was to determine the rate of Helicobacter pylori infection in preschool children of the Canton of St. Gallen, eastern Switzerland. A 13C-urea breath test was performed in 432 randomly selected 5- to 7-year-old children from February to September 1998. A total prevalence of 6.5% was found, with 3.9% for Swiss children and 19.2% for children of parents immigrated from countries or regions with a high prevalence of Helicobacter pylori infection. Children born in these countries and who immigrated later were Helicobacter pylori positive in 70%. In 20/21 brother and sister pairs, the status of Helicobacter pylori infection was concordant. The amount of living space per person and the educational level of parents were comparable for all Helicobacter pylori positive children (Swiss and immigrants). In conclusion, total prevalence of Helicobacter pylori infection in preschool children aged 5 to 7 is low in the eastern part of Switzerland, with a significantly higher rate in children of immigrant parents.
无症状瑞士儿童幽门螺杆菌感染的流行情况尚不清楚。本研究的目的是确定瑞士东部圣加仑州学龄前儿童幽门螺杆菌感染率。1998年2月至9月，对432名随机选取的5至7岁儿童进行了13C尿素呼气试验。总感染率为6.5%，瑞士儿童为3.9%，父母从幽门螺杆菌感染率高的国家或地区移民而来的儿童为19.2%。出生在这些国家后来移民的儿童中，70%幽门螺杆菌呈阳性。在20/21对兄弟姐妹中，幽门螺杆菌感染状况是一致的。所有幽门螺杆菌阳性儿童（瑞士儿童和移民儿童）的人均居住面积和父母教育水平相当。总之，瑞士东部5至7岁学龄前儿童幽门螺杆菌感染的总流行率较低，移民父母的儿童感染率明显较高。
