Wieser F, Albrecht A, Kurz C, Wenzl R, Nagele F
Abteilung für gynäkologische Endokrinologie und Sterilitätsbehandlung, Universitätsklinik für Frauenheilkunde, Wien, Osterreich.
Wien Klin Wochenschr. 1999 Apr 9;111(7):289-93.
Diagnostic hysteroscopy is the most precise procedure to evaluate diseases involving the uterine cavity. There is, however, only limited data concerning the use of hysteroscopy carried out as an outpatient procedure in patients with postmenopausal bleeding.
In this study we report on 360 postmenopausal patients with erratic bleeding, who were referred to our outpatient hysteroscopy clinic. 185 women had frank postmenopausal bleeding (PMB) and another 175 had abnormal uterine bleeding while taking hormone replacement therapy (AUB). The mean age was 57.9 years (range: 42-86). All hysteroscopies were performed using a standard 5-mm hysteroscope with a 30 degrees fore-oblique lens; the uterine cavity was generally distended with normal saline.
Outpatient hysteroscopy was performed successfully in 339 patients (94.2%). In 166 cases (46.1%) cervical dilatation was necessary, and 138 required (38.3%) intracervical anaesthesia. Intrauterine pathology was diagnosed in 49.6% of cases, with endometrial polyps (20.9%) and fibroids (15.9%) being the most common abnormalities. While there was no difference in the incidence of intrauterine lesions between patients with AUB and those with PMB, endometrial carcinoma was more common in the latter group (PMB: n = 11 vs. AUB: n = 1; p < 0.002).
Due to its high accuracy and patient acceptance, outpatient diagnostic hysteroscopy should become a first line investigation in postmenopausal patients with bleeding disorders.
诊断性宫腔镜检查是评估涉及子宫腔疾病的最精确方法。然而,关于门诊对绝经后出血患者进行宫腔镜检查的数据有限。
在本研究中,我们报告了360例绝经后出现不规则出血的患者,这些患者被转诊至我们的门诊宫腔镜检查诊所。185名女性有明显的绝经后出血(PMB),另外175名在接受激素替代治疗时出现异常子宫出血(AUB)。平均年龄为57.9岁(范围:42 - 86岁)。所有宫腔镜检查均使用标准的5毫米宫腔镜,带有30度前斜透镜;子宫腔通常用生理盐水扩张。
339例患者(94.2%)成功进行了门诊宫腔镜检查。166例(46.1%)需要宫颈扩张,138例(38.3%)需要宫颈内麻醉。49.6%的病例诊断出子宫内病变,子宫内膜息肉(20.9%)和肌瘤(15.9%)是最常见的异常情况。虽然AUB患者和PMB患者子宫内病变的发生率没有差异,但子宫内膜癌在后一组中更常见(PMB:n = 11 vs. AUB:n = 1;p < 0.002)。
由于其高准确性和患者接受度,门诊诊断性宫腔镜检查应成为绝经后出血性疾病患者的一线检查方法。