Breen N, Wesley M N, Merrill R M, Johnson K
Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892-7344, USA.
Ethn Dis. 1999 Winter;9(1):111-25.
Black women are more likely to be diagnosed with later stage breast cancer and have higher mortality rates from breast cancer than white women. To determine whether cancer treatment varies for white and black women, we analyzed data from the National Cancer Institute (NCI) Black-White Cancer Survival Study (BWCSS). Data from hospital medical records, central review of histology slides, and patient interviews on 861 breast cancer cases (in situ and invasive) were examined. Minimum expected therapy was defined for each disease stage as a basic minimum course of treatment that incorporated current practice, state-of-the-art knowledge, and recommendations advanced by NIH Consensus Conferences up to and including the one held in 1985. Patients in this study were diagnosed during 1985-1986. Using logistic regression techniques, those who received at least the minimum expected therapy were compared to those who did not. Thirty-six percent of the patients with late stage disease did not receive minimum expected therapy compared to four percent of the patients with early stage disease. Older women and women with no usual source of care were significantly less likely to receive minimum expected therapy. Overall, 21% of black women did not receive minimum expected therapy compared to 15% of white women.
黑人女性比白人女性更有可能被诊断出患有晚期乳腺癌,且因乳腺癌导致的死亡率更高。为了确定白人女性和黑人女性的癌症治疗情况是否存在差异,我们分析了美国国家癌症研究所(NCI)黑白癌症生存研究(BWCSS)的数据。研究考察了来自861例乳腺癌病例(原位癌和浸润性癌)的医院病历数据、组织学切片的集中审查结果以及患者访谈内容。每个疾病阶段的最低预期治疗方案被定义为一个基本的最低治疗疗程,该疗程纳入了当前的治疗实践、最新的知识以及美国国立卫生研究院(NIH)共识会议(直至并包括1985年举行的会议)提出的建议。本研究中的患者于1985年至1986年期间被诊断。使用逻辑回归技术,将那些接受了至少最低预期治疗的患者与未接受的患者进行比较。晚期疾病患者中有36%未接受最低预期治疗,而早期疾病患者中这一比例为4%。老年女性以及没有固定医疗来源的女性接受最低预期治疗的可能性显著更低。总体而言,21%的黑人女性未接受最低预期治疗,而白人女性的这一比例为15%。