Zobel C, Deutsch H J, Lindner M, Höpp H W, Erdmann E
Klink III für Innere Medizin, Universität zu Köln.
Dtsch Med Wochenschr. 1999 May 7;124(18):556-60. doi: 10.1055/s-2007-1024359.
A 31-year-old woman presented in the 25th week of pregnancy with ankle and pretibial oedema and increasing dyspnoea, ultimately in class IV (New York Heart Association classification). There were fine rales on auscultation and dullness on palpation over both lung bases. The heart rate was regular at 110/min. The first heart sound was very loud, and there was a mitral opening snap and a loud diastolic murmur maximal, over the cardiac apex.
The ECG showed sinus rhythm at a rate of 110/min, left axis deviation, incomplete right bundle branch block and P biatriale, but no other abnormalities. Echocardiography revealed biatrial enlargement and an enlarged right ventricle as well as pulmonary systolic hypertension of 100 mm Hg. Doppler sonography demonstrated severe mitral stenosis with a calculated mitral opening area of 0.9 cm2.
DIAGNOSIS, TREATMENT AND COURSE: The symptoms improved only slightly under conservative drug treatment. The mitral valve changes, as noted sonographically, met the criteria for percutaneous transluminal balloon mitral valvoplasty (PTBMV), which was successfully performed. Afterwards the mitral opening area was 2.6 cm2 and pulmonary artery pressure gradually became normal. She was delivered without complication of a healthy child in the 39th week of pregnancy.
PTBLMV is a relatively low-risk treatment in pregnant women with symptomatic mitral stenosis.
一名31岁女性在妊娠第25周时出现踝部及胫前水肿,呼吸困难进行性加重,最终达到纽约心脏协会心功能分级IV级。双肺底部听诊可闻及细湿啰音,触诊有浊音。心率规则,为110次/分钟。第一心音非常响亮,可闻及二尖瓣开瓣音及在心尖部最响亮的舒张期杂音。
心电图显示窦性心律,心率110次/分钟,电轴左偏,不完全性右束支传导阻滞及双房P波,但无其他异常。超声心动图显示双房增大、右心室增大以及肺动脉收缩压为100 mmHg。多普勒超声显示重度二尖瓣狭窄,计算得出二尖瓣开口面积为0.9 cm²。
诊断、治疗及病程:在保守药物治疗下症状仅稍有改善。超声检查所见的二尖瓣改变符合经皮腔内球囊二尖瓣成形术(PTBMV)标准,遂成功实施该手术。术后二尖瓣开口面积为2.6 cm²,肺动脉压力逐渐恢复正常。她在妊娠第39周顺利分娩一名健康婴儿,无并发症。
PTBLMV对于有症状的二尖瓣狭窄孕妇是一种相对低风险的治疗方法。