Ledesma Velasco M, Ibarra Flores M, Campos Santaolalla A, Acosta Valdéz J L, Abundes Velasco A, Solórzano Zepeda F J, Arizmendi Uribe E, Tello Osorio R, Farell Campa J, Verdín Vázquez R
Hospital de Cardiología Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, México, D.F.
Arch Inst Cardiol Mex. 1993 Jul-Aug;63(4):335-8.
From March 1986 to January 1993, we performed percutaneous balloon mitral commissurotomy (PBMC) in ninety-one patients with rheumatic mitral stenosis, two of them during pregnancy. The gestational age at the time of valvotomy was thirty and twenty-seven weeks respectively. Balloon Inoue technique in both cases resulted in improvement in mitral valve area (0.8 vs 1.6 and 0.7 vs 1.9 cm2) and in mean mitral gradient (19 vs 4 and 12 vs 0 mm Hg) immediately after dilation, without residual atrial septal defect or mitral insufficiency. There were no complications. The estimated radiation exposure to the fetus was of 6.4 minutes of fluoroscopy and 6 seconds of angiography. To limit of X-ray irradiation, we used color Doppler echocardiography during dilatation in both cases. The subsequent course of gestation was uncomplicated and normal babies were delivered in both cases. Fetus protection against ionising radiation was assured by lead mantles. In the follow-up the mitral valve area was 1.7 and 2.1 cm2, 15 and 4 months later respectively. PBMC can be performed safely during pregnancy and is effective in increasing the valvular area and relieving symptoms. It offers an excellent alternative for the pregnant patients, with severe mitral stenosis. The risk to the fetus appears lower than previous reports of surgical commissurotomy performed during pregnancy.
1986年3月至1993年1月,我们对91例风湿性二尖瓣狭窄患者实施了经皮球囊二尖瓣交界切开术(PBMC),其中2例在孕期进行。瓣膜切开时的孕周分别为30周和27周。两例均采用Inoue球囊技术,扩张后二尖瓣瓣口面积立即改善(分别从0.8 vs 1.6和0.7 vs 1.9 cm²),平均二尖瓣压差也改善(分别从19 vs 4和12 vs 0 mmHg),且无残余房间隔缺损或二尖瓣关闭不全。无并发症发生。估计胎儿所受的辐射暴露为透视6.4分钟和血管造影6秒。为限制X线照射,两例在扩张过程中均使用了彩色多普勒超声心动图。随后的孕期过程无并发症,两例均分娩出正常婴儿。通过铅衣确保了胎儿免受电离辐射。随访时,二尖瓣瓣口面积分别在15个月和4个月后为1.7和2.1 cm²。经皮球囊二尖瓣交界切开术在孕期可安全实施,能有效增加瓣膜面积并缓解症状。对于重度二尖瓣狭窄的孕妇患者,它提供了一个极佳的选择。胎儿所面临的风险似乎低于先前关于孕期实施外科交界切开术的报道。