Zinkevich O D, Bondarenko V M, Delian V Iu, Pikuza O I, Safina N a, Platonova O A
Research Institute of Epidemiology and Microbiology, State Medical University, Kazan, Russia.
Zh Mikrobiol Epidemiol Immunobiol. 1999 Mar-Apr(2):65-8.
The state of antibacterial humoral immunity in young children with acute bronchitis, acute obstructive bronchitis and bronchial asthma at the period of exacerbation has been shown with the use of the enzyme immunoassay. The concentration of antibodies to endotoxin positively correlates with the severity of clinical manifestations of the endogenic intoxication of the body. As the inflammatory process in the bronchial tree increases, the spectrum bacterial agents to which elevated concentrations of specific antibodies can be detected becomes wider, and this finds its maximum reflection in bronchial asthma.
利用酶免疫测定法显示了急性支气管炎、急性阻塞性支气管炎和支气管哮喘患儿在病情加重期的抗菌体液免疫状态。内毒素抗体浓度与机体内源性中毒临床表现的严重程度呈正相关。随着支气管树炎症过程的加重，可检测到特异性抗体浓度升高的细菌种类范围变宽，这在支气管哮喘中表现得最为明显。
