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巨大颈纵隔脂肪瘤。1例临床病例。

Giant cervico-mediastinal lipoma. A clinical case.

作者信息

Cutilli T, Schietroma M, Marcelli V A, Ascani G, Corbacelli A

出版信息

Minerva Stomatol. 1999 Jan-Feb;48(1-2):23-8.

Abstract

The lipoma is a circumscribed mesenchymal tumour originating from adipose tissue. The lesion is usually small and asymptomatic, and is most frequently located in the neck region. The case of a 77-year-old woman with chronic extrasystolic arrhythmia caused by a non-specified ischemic cardiopathy is reported. The woman presented a swelling at the front of her neck, observed for the first time about 6 months previously. This swelling progressively increased in size, provoking dysphagia, dysphonia, persistent cough, dyspnea, light jugular turgor and palpitations. Chest X-rays showed and opaque area at the front of the neck, which extended beyond the jugular incisure by about 2 cm. NMR of the neck showed a gross lipomatous formation at the front, mainly of the left, continuing in the front mediastinal region; the trachea was dislocated to the right and compressed at the back; the vasculo-nervous fasciculus, especially on the left, was compressed and enveloped by the adipose formation. The Holter test confirmed the presence of ventricular and supra-ventricular extrasystoles. Surgery was carried out under local anaesthesia because the displacement of the laryngo-tracheal axes precluded intubation. Histological analysis of the 9 x 4 x 2.2 cm mass confirmed the diagnosis of lipoma. After removal of the mass all the symptoms, which had been provoked by compression, as well as the cardiac arrhythmias disappeared. The prompt disappearance of the latter was particularly surprising. The possibility of the external compression of the nervous structures of the neck should be taken into consideration in cases of ventricular arrhythmia of unknown origin, and systematic study of the region carried out.

摘要

脂肪瘤是一种起源于脂肪组织的局限性间叶组织肿瘤。该病变通常较小且无症状,最常见于颈部区域。本文报告了一例77岁女性患者,患有由未明确的缺血性心脏病引起的慢性早搏性心律失常。该女性患者颈部前方出现肿胀,首次发现约在6个月前。此肿胀大小逐渐增加,引发吞咽困难、声音嘶哑、持续性咳嗽、呼吸困难、轻度颈静脉怒张和心悸。胸部X线显示颈部前方有一不透光区域,超出颈静脉切迹约2 cm。颈部核磁共振显示前方有一大块脂肪瘤形成,主要在左侧,并延续至前纵隔区域;气管向右移位并在后方受压;血管神经束,尤其是左侧的,被脂肪组织压迫并包裹。动态心电图监测证实存在室性和室上性早搏。由于喉气管轴移位妨碍插管,手术在局部麻醉下进行。对9×4×2.2 cm大小的肿块进行组织学分析,确诊为脂肪瘤。切除肿块后,所有由压迫引起的症状以及心律失常均消失。后者迅速消失尤其令人惊讶。对于不明原因的室性心律失常病例,应考虑颈部神经结构受到外部压迫的可能性,并对该区域进行系统检查。

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