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[新生期去势大鼠下丘脑的核测量法研究]

[Study of the hypothalamus of neonatally castrated rats by the karyometric method].

作者信息

Borisova N A, Stefanov S B

出版信息

Ontogenez. 1976;7(4):373-7.

PMID:1035792
Abstract

The sensitivity of different hypothalamic regions to the effect of androgens has been studied during the period of the brain sex differentiation. The castration of animals during the first week of life was shown to result in the marked increase of size of the neuron nuclei in the preoptic, suprachiasmatic, arcuate and ventromedial nuclei of the hypothalamus; the size of neuron nuclei in the dorsomedial nucleus suffered no changes. The dynamics of size of the cell nuclei was followed in different hypothalamic regions with respect to the time of castration.

摘要

在脑性别分化期间,已对不同下丘脑区域对雄激素作用的敏感性进行了研究。结果表明,在出生后第一周对动物进行阉割会导致下丘脑视前核、视交叉上核、弓状核和腹内侧核中神经元细胞核大小显著增加;背内侧核中神经元细胞核大小未发生变化。针对阉割时间,对不同下丘脑区域细胞核大小的动态变化进行了跟踪研究。

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