[Changes in the amount of protein in hypothalamic neurons of sexually mature rats castrated neonatally].

A change in the amount of protein in the neurons of the anterior and mediobasal hypothalamus of sexually mature male rats castrated neonatally was observed in the study using the interferometric method. A considerable increase was recorded in the dry weight of the neurons in the medial preoptic region and the arcuate and ventromedial nuclei of the hypothalamus. The most pronounced changes were observed in the nuclei of these neurons. The results obtained point to the influence of androgens on the hypothalamic structures responsible for the regulation of both cyclic and tonic release of gonadotropic hormones in sexually mature animals during sex differentiation of the brain.