胰岛素对α-肾上腺素能作用于肝糖原代谢的拮抗作用。
Insulin counteraction of alpha-adrenergic effects on liver glycogen metabolism.
作者信息
Massagué J, Guinovart J J
出版信息
Biochim Biophys Acta. 1978 Oct 3;543(2):269-72. doi: 10.1016/0304-4165(78)90073-9.
PMID:103580
Abstract
Insulin counteracted the effects of a pure alpha-adrenergic agonist, phenylephrine, on hepatocyte glycogen synthase and phosphorylase. These results argue against current concepts of insulin increasing cytoplasmic Ca2+ concentration.
摘要
胰岛素抵消了纯α-肾上腺素能激动剂去氧肾上腺素对肝细胞糖原合酶和磷酸化酶的作用。这些结果与当前关于胰岛素增加细胞质钙离子浓度的概念相悖。
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