Am J Infect Control. 1999 Jun;27(3):279-84. doi: 10.1053/ic.1999.v27.a98878.
The Intensive Care Antimicrobial Resistance Epidemiology project has established laboratory-based surveillance for antimicrobial resistance and antimicrobial use at a subset of hospitals participating in the National Nosocomial Infections Surveillance system. These data illustrate that, for most antimicrobial resistant organisms studied, rates of resistance were highest in the intensive care unit areas and lowest in the outpatient areas. For most of the antimicrobial agents, the rate of use was highest in the intensive care unit areas in parallel to the pattern seen for resistance. These comparative data on antimicrobial use and resistance among similar areas (ie, intensive care unit or other inpatient areas) can be used as a benchmark by participating hospitals to focus their efforts at addressing antimicrobial resistance.
重症监护抗菌药物耐药性流行病学项目已在参与国家医院感染监测系统的部分医院建立了基于实验室的抗菌药物耐药性及抗菌药物使用监测。这些数据表明，对于所研究的大多数抗菌药物耐药菌而言，重症监护病房区域的耐药率最高，门诊区域的耐药率最低。对于大多数抗菌药物，其使用频率在重症监护病房区域也是最高的，与耐药情况呈现的模式一致。这些关于相似区域（即重症监护病房或其他住院区域）抗菌药物使用和耐药性的比较数据，可供参与项目的医院用作基准，以集中精力应对抗菌药物耐药性问题。
