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[经腹腔接种绵羊衣原体的小鼠的顿挫感染]

[Abortive infection of mice inoculated intraperitoneally with Chlamydia ovis].

作者信息

Rodolakis A

出版信息

Ann Rech Vet. 1976;7(2):195-205.

PMID:1035841
Abstract

A mouse adaptated strain of Chlamydia ovis, when inoculated in the peritoneal cavity, caused the death of both pregnant and non pregnant mice. In addition, mice inoculated late in pregnancy (12 to 16 days after breeding) aborted 4 to 6 days after inoculation. Chlamydia was recovered from foetuses and from the organs of the mice (Liver, Spleen, Lungs). The severity of the disease was related to the inoculum concentration, so it was possible to induce late abortions with a rapid recovery of the females, like in the natural infection of the ewes. In the same conditions, the original Chlamydia strain maintained by passage on yolk sac, induced only an inapparent disease transmissible to the young mice.

摘要

一种绵羊衣原体的小鼠适应株,接种于腹腔时,可导致怀孕和未怀孕小鼠死亡。此外,在怀孕后期(交配后12至16天)接种的小鼠在接种后4至6天流产。从胎儿和小鼠器官(肝脏、脾脏、肺)中分离出衣原体。疾病的严重程度与接种物浓度有关,因此有可能诱导晚期流产,且雌性小鼠能快速恢复,就像母羊自然感染时一样。在相同条件下,通过卵黄囊传代保存的原始衣原体菌株仅引起一种可传染给幼鼠的隐性疾病。

相似文献

1
[Abortive infection of mice inoculated intraperitoneally with Chlamydia ovis].[经腹腔接种绵羊衣原体的小鼠的顿挫感染]
Ann Rech Vet. 1976;7(2):195-205.
2
Clinical evaluation of a commercial vaccine against chlamydial abortion of ewes.一种用于预防母羊衣原体流产的商业疫苗的临床评估。
Ann Rech Vet. 1979;10(1):41-8.
3
[Chlamydia as the cause of abortions in horses].[衣原体作为马流产的病因]
Berl Munch Tierarztl Wochenschr. 1991 Apr 1;104(4):119-24.
4
[Bacteriologic studies of aborted sheep fetuses with special reference to chlamydiae].[流产绵羊胎儿的细菌学研究,特别涉及衣原体]
Tierarztl Prax. 1991 Oct;19(5):475-9.
5
Diagnosis of ovine vibriosis and enzootic abortion of ewes by immunofluorescence technique.用免疫荧光技术诊断绵羊弧菌病和母羊地方性流产
Am J Vet Res. 1972 Dec;33(12):2535-8.
6
[Can Chlamydia trachomatis human biovars cause abortion in cattle? An immunohistochemical study on a new host-pathogen relationship].[沙眼衣原体人生物变种会导致牛流产吗?关于一种新的宿主-病原体关系的免疫组织化学研究]
Mikrobiyol Bul. 2008 Oct;42(4):599-605.
7
Lambing performance of ewes inoculated with Chlamydia sp. before and after breeding.在配种前后接种衣原体属的母羊的产羔性能。
Am J Vet Res. 1971 May;32(5):809-11.
8
[Demonstration of Chlamydia from an equine abortion].[从马流产病例中检测到衣原体]
Dtsch Tierarztl Wochenschr. 2000 Feb;107(2):49-52.
9
Abortion in dairy cows inoculated with epizootic bovine abortion agent (Chlamydia).
Am J Vet Res. 1971 May;32(5):703-10.
10
[Experimental infection of the pregnant cow with Chlamydia psittaci].[鹦鹉热衣原体对怀孕母牛的实验性感染]
Ann Rech Vet. 1983;14(2):117-20.

引用本文的文献

1
Host adaptation of Chlamydia pecorum towards low virulence evident in co-evolution of the ompA, incA, and ORF663 Loci.在ompA、incA和ORF663基因座的共同进化中,猪衣原体对低毒力的宿主适应性明显。
PLoS One. 2014 Aug 1;9(8):e103615. doi: 10.1371/journal.pone.0103615. eCollection 2014.
2
In vitro and in vivo properties of chemically induced temperature-sensitive mutants of Chlamydia psittaci var. ovis: screening in a murine model.鹦鹉热衣原体羊变种化学诱导温度敏感突变体的体外和体内特性:在小鼠模型中的筛选
Infect Immun. 1983 Nov;42(2):525-30. doi: 10.1128/iai.42.2.525-530.1983.