Vykouril J, Lukás Z, Balák V, Pavlousková A
Interní oddĕlení Nemocnice, Tisnov.
Vnitr Lek. 1998 Sep;44(9):551-4.
The authors describe a case of Whipple's disease diagnosed early during gastroduodenofibroscopy from a bioptioc specimen of the prepyloric gastric mucosa, and treated in time. The disease was complicated by superinfection with Salmonella enteritidis. In the clinical picture digestive symptoms predominated, loose stools, malabsorption, loss of body weight, anaemia, skin pigmentation. After antibiotic and later chemotherapeutic treatment clinical symptoms receded and the histological finding in bioptic specimens from the stomach was normal.
作者描述了一例惠普尔病，通过对幽门前胃黏膜活检标本进行纤维十二指肠镜检查早期诊断，并及时进行了治疗。该疾病合并肠炎沙门氏菌二重感染。临床表现以消化症状为主，包括腹泻、吸收不良、体重减轻、贫血、皮肤色素沉着。经过抗生素及后续化疗，临床症状消退，胃活检标本的组织学检查结果恢复正常。
