Tepmongkol S, Heyman S
Department of Radiology, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn's Memorial Hospital, Bangkok, Thailand.
Med Pediatr Oncol. 1999 Jun;32(6):427-31; discussion 432. doi: 10.1002/(sici)1096-911x(199906)32:6<427::aid-mpo6>3.0.co;2-t.
131I MIBG has been used as palliative treatment of neuroblastoma patients with recurrent or persistent disease who failed other modalities of treatment. Since the results were promising, the concept arose of using it in conjunction with other modalities, either as an up-front treatment or as combination therapy. This article reviews the principle of 131I MIBG treatment, in conjunction with other modalities currently used for the treatment of neuroblastoma, in an attempt to improve the final outcome.
131I 间碘苄胍已被用作治疗复发性或持续性神经母细胞瘤且其他治疗方式失败的患者的姑息治疗。由于结果令人鼓舞，于是出现了将其与其他治疗方式联合使用的概念，既可以作为一线治疗，也可以作为联合治疗。本文回顾了131I 间碘苄胍治疗的原理，并结合目前用于治疗神经母细胞瘤的其他治疗方式，试图改善最终治疗效果。
