Daneholt B
Department of Cell and Molecular Biology, Medical Nobel Institute, Karolinska Institute, SE-17177 Stockholm, Sweden.
Curr Biol. 1999 Jun 3;9(11):R412-5. doi: 10.1016/s0960-9822(99)80256-5.
It has been difficult to establish whether pre-messenger ribonucleoprotein (pre-mRNP) particles move from the gene towards the periphery of the nucleus in a directed or random manner. Two recent in vivo studies indicate that most pre-mRNP particles move randomly in the nucleus, apparently by free diffusion.
一直以来,很难确定信使核糖核酸前体(pre-mRNP)颗粒是以定向还是随机的方式从基因向细胞核周边移动。最近的两项体内研究表明,大多数pre-mRNP颗粒在细胞核内随机移动,显然是通过自由扩散。