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[母体甲状腺功能亢进时子代甲状腺和甲状旁腺的形态功能特征]

[Morphofunctional characteristics of the thyroid and parathyroid glands of the progeny in the presence of maternal hyperthyroidism].

作者信息

Detiuk E S

出版信息

Arkh Anat Gistol Embriol. 1976;71(11):100-4.

PMID:1036015
Abstract

The posterity of female albino rats given di-thyroxin (15 mkg/100 g) during gestation and lactation differ from off-springs of intact rats by less body weight and increased gas-exchange. Their thyroid galnds show evident signs of functional suppression, e. g. decreased relative weight, diminished height of thyrocytes, cytochemical shifts in the content and topography of RNP and the ascorbic acid. During the first 30 days of the postnatal life the parathyroid glands have greater weight than controls, are characterized by a number of morphological and cytochemical signs suggesting their increased functioning.

摘要

在妊娠和哺乳期给予双甲状腺素(15微克/100克)的雌性白化大鼠的后代,与正常大鼠的后代相比,体重较轻且气体交换增加。它们的甲状腺显示出明显的功能抑制迹象,例如相对重量降低、甲状腺细胞高度减小、核糖核蛋白(RNP)和抗坏血酸含量及分布的细胞化学变化。在出生后的前30天,甲状旁腺比对照组重,具有许多形态学和细胞化学特征,表明其功能增强。

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