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[伴睡眠性呼吸困难的延髓背外侧综合征——病例研究]

[Wallenberg's syndrome with sleep-induced dyspnea--a case study].

作者信息

Ikeda H, Hori M, Mogami H

出版信息

No To Shinkei. 1976 Nov;28(11):1259-64.

PMID:1036029
Abstract

One case with Wallenberg's syndrome followed by the neck clipping of the posterior inferior cerebellar aneurysm was reported. The patient was 49 years old female with the subarachnoid hemorrhage, who had previously no history of the cardiovascular disease. The vertebral angiogram revealed a saccular aneurysm of the left vertebral artery at the origin of the posterior inferior cerebellar artery. The preoperative neurological examination were normal, except for the slight degree of the meningeal irritation. The surgical intervention was successfully performed on 39th day after the subarachnoid hemorrhage. Postoperative course was eventful, presenting the typical Wallenberg's syndrome, which was complicated the accompanying signs. The troublesome accompanying signs were chiefly automatic respiratory dysfunction (sleep-induced dyspnea), autonomic dysfunction (Horner's syndrome, perspiration, hypertension), and restless confusion. The postoperative vertebral angiogram showed the obliteration of the aneurysm and the sufficient circulation of the vertebrobasilar system, especially the posterior inferior cerebellar artery. The mechanism of "sleep-induced dyspnea" was discussed in detail from the literatures. In addition to the above mentioned, it should be stressed that the recognition of "sleep-induced dyspnea" and the other accompanying signs are important for the treatment of the patient with the brain stem lesion.

摘要

报告了1例伴有延髓背外侧综合征的患者,该患者接受了小脑后下动脉瘤颈部夹闭术。患者为49岁女性,有蛛网膜下腔出血病史,既往无心血管疾病史。椎动脉血管造影显示左椎动脉在小脑后下动脉起源处有一个囊状动脉瘤。术前神经学检查正常,仅有轻度脑膜刺激征。在蛛网膜下腔出血后第39天成功进行了手术干预。术后病程多变,出现典型的延髓背外侧综合征,并伴有相关体征。麻烦的伴随体征主要有自动呼吸功能障碍(睡眠性呼吸困难)、自主神经功能障碍(霍纳综合征、出汗、高血压)和烦躁不安。术后椎动脉血管造影显示动脉瘤闭塞,椎基底动脉系统,尤其是小脑后下动脉循环良好。从文献中详细讨论了“睡眠性呼吸困难”的机制。除此之外,应强调的是,认识“睡眠性呼吸困难”和其他伴随体征对脑干病变患者的治疗很重要。

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