Kwon B M, Kim M K, Baek N I, Kim D S, Park J D, Kim Y K, Lee H K, Kim S I
Korea Research Institute of Bioscience and Biotechnology, Yusung, Taejon.
Bioorg Med Chem Lett. 1999 May 17;9(10):1375-8. doi: 10.1016/s0960-894x(99)00208-5.
Ginseng sapogenins were produced from ginseng saponins, isolated from Korean ginseng roots. Ginseng saponins very mildly inhibited acyl-CoA:cholesterol acyltransferase (ACAT) in vitro, however, the sapogenins showed strong inhibitory activity on microsomal ACAT. Therefore, the sapogenins will be one of key ingredients of ginseng affected a lowering of the serum total cholesterol level.
人参皂苷元由从高丽参根中分离得到的人参皂苷制备而来。人参皂苷在体外对酰基辅酶A：胆固醇酰基转移酶（ACAT）有非常轻微的抑制作用，然而，皂苷元对微粒体ACAT表现出较强的抑制活性。因此，皂苷元将是人参中影响血清总胆固醇水平降低的关键成分之一。
