Gentile G, Mele A, Ragona G, Faggioni A, Zompetta C, Tosti M E, Visani G, Castelli G, Pulsoni A, Monarca B, Martino P, Mandelli F
Dipartimento di Biotecnologie Cellulari e Ematologia, Università La Sapienza, Roma, Italia.
Br J Cancer. 1999 Jun;80(7):1103-6. doi: 10.1038/sj.bjc.6690471.
The relationships between acute myeloid leukaemia (AML), acute lymphocytic leukaemia (ALL), chronic myeloid leukaemia (CML) and refractory anaemia with excess of blasts (RAEB) and human herpes virus (HHV)-6 antibody level were investigated in a multicentre case-control study. An association between increased HHV-6 seropositivity and geometric mean titre ratio with AML was shown: P for trend = 0.022, adjusted odds ratio 1.20, 95% confidence interval 1.07-1.33 respectively. No association was found between HHV-6 and ALL, CML or RAEB.
在一项多中心病例对照研究中，对急性髓系白血病（AML）、急性淋巴细胞白血病（ALL）、慢性髓系白血病（CML）以及伴有原始细胞增多的难治性贫血（RAEB）与人类疱疹病毒（HHV）-6抗体水平之间的关系进行了研究。结果显示，HHV-6血清阳性率及几何平均滴度比值升高与AML之间存在关联：趋势P值=0.022，校正比值比为1.20，95%置信区间分别为1.07 - 1.33。未发现HHV-6与ALL、CML或RAEB之间存在关联。
