Menéndez-Patterson A, Florez-Lozano J A, Marin B
Reproduccion. 1976 Jul-Dec;3(3-4):287-93.
The metabolic-oxidative activity of different nervous and glandular structures (amygdala, hypothalamus, lateral-frontal cerebral cortex, adrenal glands) in male and female rats under acute stress caused by physical immobilization, was determined. The sexual cycle of the female rat was controlled by examination of their vaginal frotis. One experimental group during estrus and another one during diestrus were selected. At the same time ovariectomy was performed on an experimental group in order to eliminate the hormonal influences of the ovary. Results show there are no significant differerneces in the oxidative metabolism. Nor in the numbers of ulcers. Hypothalamus-hypophyseal-adrenocortical activation was made manifest on obtaining significant differences in the weight of the adrenal glands, a fact long ago reported in a number of studies. Necropsy showed severe gastric hemorrhages and ulcer in the stomach. Nevertheless, no significant differences between the distinc experimental groups were obtained. The likely participation of sexual hormones in female rats is discussed in the light of our results.
测定了雄性和雌性大鼠在物理固定引起的急性应激下，不同神经和腺体结构（杏仁核、下丘脑、额叶外侧大脑皮层、肾上腺）的代谢氧化活性。通过检查雌性大鼠的阴道涂片来控制其性周期。选择了发情期的一个实验组和动情间期的另一个实验组。同时，对一个实验组进行卵巢切除术，以消除卵巢的激素影响。结果表明，氧化代谢和溃疡数量均无显著差异。肾上腺重量出现显著差异，表明下丘脑 - 垂体 - 肾上腺皮质激活，这一事实在许多研究中早已报道。尸检显示胃有严重出血和溃疡。然而，不同实验组之间未获得显著差异。根据我们的结果，讨论了性激素在雌性大鼠中的可能作用。
