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雌性大鼠唾液腺切除和去势的影响。

Effects of sialoadenectomy and castration in female rats.

作者信息

Menéndez-Patterson A, Velasco-Plaza A, Marin B

出版信息

Reproduccion. 1982 Jan-Mar;6(1):19-27.

PMID:6889545
Abstract

Previous work on the role of the submaxillary glands in the control of the oestrous cycle in rats has been extended to castrated rats in order to avoid the overlapping between sexual and salivary hormones. Animals were sacrificed 30 days after sialadectomy or pseudosialadectomy. The data show that simultaneous castration and sialadectomy increases significantly the glucaemia level and decreases the weight of the adrenal glands. Non-simultaneous castration and removal of the submaxillary glands decreases the weight of the parotid glands. This effect decreases when both actions are simultaneous. On the other hand, castration produces an important decrease in QO2 uptake in tested structures. Removal of submaxillary glands produces a significant increase of QO2 in hypothalamus and thyroid glands. Simultaneous castration and sialadectomy at the anterior cortex, posterior cortex and parotid gland level shows similar results with respect to desalivated rats; other structures show results similar to the castrated group values. From these results, the role played by submaxillary glands in the control of the sexual cycle of the rat and the possible relation to other structures is discussed.

摘要

先前关于大鼠颌下腺在发情周期控制中作用的研究已扩展至去势大鼠,以避免性激素和唾液激素之间的相互干扰。在涎腺切除或假涎腺切除术后30天处死动物。数据表明,同时去势和涎腺切除会显著提高血糖水平并降低肾上腺重量。非同时进行去势和颌下腺切除会降低腮腺重量。当两种操作同时进行时,这种影响会减弱。另一方面,去势会使受试结构的耗氧量显著降低。切除颌下腺会使下丘脑和甲状腺的耗氧量显著增加。在前皮质、后皮质和腮腺水平同时进行去势和涎腺切除,其结果与去涎腺大鼠相似;其他结构的结果与去势组的值相似。基于这些结果,讨论了颌下腺在大鼠性周期控制中所起的作用以及与其他结构的可能关系。

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