墨汁鬼伞提取物的双硫仑样生物活性再研究。

Reinvestigation of disulfiram-like biological activity of Coprinus atramentarius (Bull. ex Fr.) Fr. extracts.

作者信息

Vanhaelen M, Vanhaelen-Fastré R, Hoyois J, Mardens Y

出版信息

J Pharm Sci. 1976 Dec;65(12):1774-6. doi: 10.1002/jps.2600651220.

Abstract

A ninhydrin-positive aqueous fraction isolated from Coprinus atramentarius (Bull. ex Fr.) Fr. showed significant disulfiram-like activity in mice. The isolation of the fraction from the mushroom crude extract and a convenient pharmacological test for following the physiological activity in each fraction are described.

摘要

从墨汁鬼伞（Bull. ex Fr.）Fr.中分离得到的茚三酮阳性水相部分在小鼠中显示出显著的双硫仑样活性。本文描述了从蘑菇粗提物中分离该部分的方法以及用于跟踪各部分生理活性的简便药理试验。