Everitt N J
General Infirmary at Leeds.
Ann R Coll Surg Engl. 1999 Mar;81(2):109-12.
Infusion thrombophlebitis is common and is the principal limitation to intravenous nutrition (IVN) via a peripheral vein, yet its precise pathogenesis is unclear. Prospective observations were performed on patients in whom a hypertonic, acidic, nutritional emulsion was infused via fine-bore polyurethane catheters placed in peripheral veins. B mode ultrasound was used to determine vein calibre and proved to be a useful means for serial examination during intravenous infusion. Contrary to previous reports, no evidence of venospasm was observed. It is suggested that previous evidence of venoconstriction is erroneous and that other mechanisms are responsible for thrombophlebitis.
输注性血栓性静脉炎很常见，是经外周静脉进行静脉营养（IVN）的主要限制因素，但其确切发病机制尚不清楚。对通过置于外周静脉的细孔聚氨酯导管输注高渗、酸性营养乳剂的患者进行了前瞻性观察。使用B型超声来确定静脉管径，事实证明这是静脉输注期间进行系列检查的一种有用方法。与先前的报告相反，未观察到静脉痉挛的迹象。有人提出，先前关于静脉收缩的证据是错误的，其他机制才是血栓性静脉炎的病因。
