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阿托品对人体口服及静脉注射葡萄糖所致胰岛素释放的影响。

The effect of atropine on the insulin release caused by oral and intravenous glucose in human subjects.

作者信息

Henderson J R, Jefferys D B, Jones R H, Stanley D

出版信息

Acta Endocrinol (Copenh). 1976 Dec;83(4):772-80. doi: 10.1530/acta.0.0830772.

DOI:10.1530/acta.0.0830772
PMID:1036650
Abstract

Oral and intravenous glucose tolerance tests were performed on normal fasting subjects, with and without atropine. Insulin release after oral glucose was significantly diminished by atropine, and this effect could not be ascribed to the drug delaying glucose absorption. However, insulin release brought about by intravenous glucose was not altered by atropine. Possible interpretations of these results are discussed.

摘要

对正常空腹受试者进行了口服和静脉葡萄糖耐量试验,试验中有的受试者使用了阿托品,有的未使用。口服葡萄糖后,阿托品显著降低了胰岛素释放,且这种作用不能归因于该药物延迟了葡萄糖吸收。然而,静脉注射葡萄糖引起的胰岛素释放并未因阿托品而改变。文中讨论了这些结果可能的解释。

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Acta Endocrinol (Copenh). 1976 Dec;83(4):772-80. doi: 10.1530/acta.0.0830772.
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