Stabile G, De Simone A, Solimene F, Turco P, Rotunno R, Di Napoli T
Laboratorio di Elettrofisiologia, Casa di Cura San Michele, Maddaloni, CE.
G Ital Cardiol. 1999 May;29(5):549-54.
Junctional beats (JB) are often recorded during slow pathway (SP) radiofrequency (RF) ablation in patients with atrioventricular nodal reentrant tachycardia (AVNRT). Neither the correlation between JBs and SP potentials nor the role of mechanically-evoked JBs has been clarified yet.
Two hundred-eleven consecutive patients, with common AVNRT, underwent RF transcatheter ablation guided by Jackman SP potential searching. If we were unable to record an SP potential or if 4 RF pulses delivered on ideal ablation sites were ineffective, the ablation was carried out on anatomical landmarks. Light pressure was applied with the ablation catheter to each ablation site before RF delivery in order to evaluate the inducibility of JBs.
Transcatheter ablation was performed successfully in 209/211 (99%) patients. In 17 (8.1%) patients, no SP potential was recorded. JBs were observed more often delivering RF in the mid-septal region, whereas SP potentials were more often recorded at the base of the Koch triangle. The success rate (successful pulses/overall pulses) was higher in the mid-septal (58.6% in M1, 77.8% in M2) than in the postero-septal region (4% in PSC, 16.8% in P1). JBs showed a higher specificity (73.2 vs 5.3%), positive (55.5 vs 24.6%) and negative predictive value (97.3 vs 63.8%) than SP potential in identifying the successful ablation site. Mechanical JBs were evoked in 23 patients on 29 ablation sites, and 18/29 (62.1%) of them were successful ablation sites.
The recording of JBs during or before RF ablation is a useful parameter to guide SP ablation in patients with AVNRT. Although the underlying mechanism has not been clarified yet, their preferential occurrence in the mid-septal region suggests that they might be due to thermal stimulation of compact atrioventricular node.
房室结折返性心动过速(AVNRT)患者在慢径路(SP)射频(RF)消融过程中常记录到交界性搏动(JB)。JB与SP电位之间的相关性以及机械诱发JB的作用尚未明确。
211例连续的普通AVNRT患者接受了在Jackman SP电位搜索指导下的经导管RF消融。如果我们无法记录到SP电位,或者在理想消融部位施加的4个RF脉冲无效,则在解剖标志处进行消融。在RF释放前,用消融导管对每个消融部位施加轻压,以评估JB的诱发性。
209/211(99%)例患者成功进行了经导管消融。17例(8.1%)患者未记录到SP电位。在中隔区域释放RF时更常观察到JB,而SP电位更常在Koch三角底部记录到。中隔区域的成功率(成功脉冲数/总脉冲数)高于后隔区域(后隔中央为4%,P1为16.8%,中隔M1为58.6%,M2为77.8%)。在识别成功消融部位方面,JB比SP电位具有更高的特异性(73.2对5.3%)、阳性(55.5对24.6%)和阴性预测值(97.3对63.8%)。23例患者在29个消融部位诱发了机械性JB,其中18/29(62.1%)为成功消融部位。
RF消融期间或之前记录JB是指导AVNRT患者SP消融的有用参数。虽然其潜在机制尚未明确,但它们在中隔区域的优先出现表明可能是由于致密房室结的热刺激所致。