González-Flecha B, Demple B
Physiology Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA.
J Bacteriol. 1999 Jun;181(12):3833-6. doi: 10.1128/JB.181.12.3833-3836.1999.
Intracellular hydrogen peroxide is regulated in Escherichia coli by OxyR in response to the metabolic production of H2O2. Here, we show that the untranslated oxyS RNA controlled by OxyR has a role in this regulation. The oxyS transcript appears to affect the metabolic output of H2O2 rather than the removal of H2O2 by catalases-hydroperoxidases.
在大肠杆菌中,细胞内过氧化氢由OxyR响应H2O2的代谢产生进行调控。在此,我们表明由OxyR控制的未翻译的oxyS RNA在这种调控中发挥作用。oxyS转录本似乎影响H2O2的代谢输出,而不是通过过氧化氢酶 - 氢过氧化物酶去除H2O2。