Suppr超能文献

微创再次冠状动脉搭桥手术的临床经验

Clinical experience with minimally invasive reoperative coronary bypass surgery.

作者信息

Subramanian V A

机构信息

Department of Surgery, Lennox Hill Hospital, New York, NY 10021, USA.

出版信息

Eur J Cardiothorac Surg. 1996;10(12):1058-62; discussion 1062-3. doi: 10.1016/s1010-7940(96)80352-6.

Abstract

OBJECTIVE

To minimize the risk of standard and reoperative coronary artery bypass, we developed a minimally invasive approach. In this study we have evaluated the effectiveness of this technique.

METHOD

Between April 1994 and September 1995, 12 men and 6 women, aged 55-84 years (mean, 69 years) with chronic stable angina (4) and recent post-myocardial infarction unstable angina (14), with left ventricular ejection fractions ranging 17-60% (mean 37%), underwent reoperative coronary artery bypass grafting using 7-cm mini-left and right anterior thoracotomy and subxiphoid incisions. Coronary artery anastomoses were carried out on beating hearts with local coronary occlusion. Ischemic preconditioning, beta and calcium channel blockers and the maintenance of mean arterial pressure at 75-80 mm Hg, were used as adjuncts for myocardial protection. The internal mammary artery was isolated under direct vision up to the second rib with excision of the fourth costal cartilage. Coronary artery target sites were the left anterior descending in 12, right coronary artery in 4, obtuse marginal in 3, posterior descending in 1 and diagonal branch in 1 patient. Arterial grafts (mammary, right gastroepiploic, radial), either as single or composite grafts, were used liberally. Preoperative risk factors included congestive heart failure (7), chronic renal insufficiency (5), second reoperation (2), third reoperation (1), cerebrovascular disease (5), prior angioplasty (8) and preoperative intra-aortic balloon pumping in two patients.

RESULTS

There was no perioperative mortality with minimal morbidity. Twelve patients underwent patency study of the grafts 48-72 h postoperatively. Ten of the twelve grafts were patent; one internal mammary artery graft to the left anterior descending coronary artery (<1.5 mm) early in our series was occluded and one additional left internal mammary graft had a kink several centimeters away from the anastomosis, which was successfully opened by angioplasty. At a mean follow-up interval of 8 months all 16 surviving patients are in functional class I or II and all of them remain free of angina.

CONCLUSION

In selected patients reoperative coronary artery bypass grafting can be performed with this minimally invasive approach with a low perioperative morbidity and mortality rate and satisfactory early graft patency rate with good symptomatic improvement.

摘要

目的

为将再次冠状动脉搭桥手术的风险降至最低,我们开发了一种微创方法。在本研究中,我们评估了该技术的有效性。

方法

1994年4月至1995年9月期间,12名男性和6名女性,年龄55 - 84岁(平均69岁),患有慢性稳定型心绞痛(4例)和近期心肌梗死后不稳定型心绞痛(14例),左心室射血分数为17% - 60%(平均37%),采用7厘米的左、右前胸小切口及剑突下切口进行再次冠状动脉搭桥手术。在心脏跳动且局部冠状动脉阻断的情况下进行冠状动脉吻合。采用缺血预处理、β受体阻滞剂和钙通道阻滞剂,并将平均动脉压维持在75 - 80毫米汞柱,作为心肌保护的辅助措施。在直视下分离胸廓内动脉至第二肋,切除第四肋软骨。冠状动脉靶点部位为左前降支12例、右冠状动脉4例、钝缘支3例、后降支1例、对角支1例。广泛使用动脉移植物(乳腺、右胃网膜、桡动脉),可单独或复合使用。术前危险因素包括充血性心力衰竭(7例)、慢性肾功能不全(5例)、二次手术(2例)、三次手术(1例)、脑血管疾病(5例)、既往血管成形术(8例)以及2例患者术前使用主动脉内球囊反搏。

结果

围手术期无死亡病例,发病率极低。12例患者在术后48 - 72小时进行了移植物通畅性研究。12根移植物中有10根通畅;在我们系列研究早期,1根连接左前降支冠状动脉的胸廓内动脉移植物(<1.5毫米)闭塞,另有1根左胸廓内动脉移植物在距吻合口几厘米处出现扭结,经血管成形术成功开通。平均随访8个月时,所有16例存活患者的心功能分级为Ⅰ级或Ⅱ级,且均无心绞痛症状。

结论

对于选定的患者,采用这种微创方法进行再次冠状动脉搭桥手术,围手术期发病率和死亡率低,早期移植物通畅率满意,症状改善良好。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验