Subramanian V A
Department of Surgery, Lenox Hill Hospital, New York, New York 10021, USA.
Ann Thorac Surg. 1997 Jun;63(6 Suppl):S68-71. doi: 10.1016/s0003-4975(97)00417-7.
Competitive status of percutaneous transluminal coronary angioplasty and stenting has stimulated an interest in minimally invasive direct coronary artery bypass grafting.
Between April 1994 and September 1996,156 patients with a mean age of 67 +/- 10 years have undergone minimally invasive direct coronary artery bypass grafting via minithoracotomy, subxiphoid incision, or both with internal mammary artery, right gastroepiploic artery, and radial artery grafting using local coronary occlusion on a beating heart with immobilization of the coronary artery target sites with traction sutures and mechanical regional cardiac wall immobilization platform.
Morbidity included wound infection (3), reoperation for bleeding (5), atrial fibrillation (12), central nervous system complication (1), and perioperative myocardial infarction (5). Cardiac-related operative mortality was 1.2% (2/156). Predominantly single grafting was done in 128 patients. Routine angiographic and Doppler echocardiographic flow assessment of anastomotic patency showed an overall patency rate of 92%. In 52 recent consecutive patients in whom the regional cardiac wall mechanical stabilization platform was used, the patency rate of the left internal mammary artery-to-left anterior descending coronary artery graft was improved to 96.2%. With a mean followup of 9.2 +/- 7.4 months, cardiac event-free interval (percutaneous transluminal coronary angioplasty, reoperative coronary artery bypass grafting, or death) in 111 patients was 91%.
Minimally invasive direct coronary artery bypass grafting is safe and effective with good early and midterm clinical results, especially with left internal mammary artery-to-left anterior descending coronary artery grafting via minithoracotomy. Regional cardiac wall immobilization of coronary artery target sites enhances the early graft patency in a predictable manner (96.2%), and this method should be an essential part of all minimally invasive direct coronary artery bypass graft operations with left internal mammary artery-to-left anterior descending artery grafts via minithoracotomy. Further study is required to establish the long-term efficacy of minimally invasive direct coronary artery bypass grafting and the treatment of coronary artery disease.
经皮腔内冠状动脉成形术及支架置入术的竞争地位激发了人们对微创直接冠状动脉旁路移植术的兴趣。
1994年4月至1996年9月期间,156例平均年龄为67±10岁的患者接受了微创直接冠状动脉旁路移植术,手术通过小切口开胸、剑突下切口或两者联合进行,采用乳内动脉、胃网膜右动脉和桡动脉进行移植,在心脏跳动时局部阻断冠状动脉,用牵引缝线固定冠状动脉靶部位,并使用机械性局部心脏壁固定平台。
并发症包括伤口感染(3例)、因出血再次手术(5例)、心房颤动(12例)、中枢神经系统并发症(1例)和围手术期心肌梗死(5例)。心脏相关手术死亡率为1.2%(2/156)。128例患者主要进行单支血管移植。常规血管造影和多普勒超声心动图对吻合口通畅情况的血流评估显示总体通畅率为92%。在最近连续使用局部心脏壁机械稳定平台的52例患者中,左乳内动脉至左前降支冠状动脉移植的通畅率提高到了96.2%。平均随访9.2±7.4个月,111例患者的无心脏事件间期(经皮腔内冠状动脉成形术、再次冠状动脉旁路移植术或死亡)为91%。
微创直接冠状动脉旁路移植术安全有效,具有良好的早期和中期临床效果,尤其是通过小切口开胸进行左乳内动脉至左前降支冠状动脉移植。冠状动脉靶部位的局部心脏壁固定以可预测的方式提高了早期移植血管通畅率(96.2%),该方法应成为所有通过小切口开胸进行左乳内动脉至左前降支动脉移植的微创直接冠状动脉旁路移植手术的重要组成部分。需要进一步研究以确定微创直接冠状动脉旁路移植术治疗冠状动脉疾病的长期疗效。