• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Microsatellite instability.

作者信息

Frayling I M

机构信息

Cambridge University Department of Medical Genetics Molecular Genetics Laboratory, Box 158 Addenbrooke's Hospital Cambridge CB2 2QQ, UK.

出版信息

Gut. 1999 Jul;45(1):1-4. doi: 10.1136/gut.45.1.1.

DOI:10.1136/gut.45.1.1
PMID:10369691
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1727570/
Abstract
摘要

相似文献

1
Microsatellite instability.微卫星不稳定性
Gut. 1999 Jul;45(1):1-4. doi: 10.1136/gut.45.1.1.
2
Microsatellite instability.微卫星不稳定性
N Engl J Med. 2003 Jul 17;349(3):209-10. doi: 10.1056/NEJMp038099.
3
[Microsatellite instability--a new aspects in genetics and molecular biology of hereditary nonpolyposis and sporadic colorectal tumors].[微卫星不稳定性——遗传性非息肉病性和散发性结直肠癌肿瘤遗传学与分子生物学的新方面]
Z Gastroenterol. 1996 Dec;34(12):813-22.
4
[Germline mutation and microsatellite instability in hereditary nonpolyposis colon carcinomas].
Z Gastroenterol. 1996 Aug;34(8):509-11.
5
Re: Revised Bethesda guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability.
J Natl Cancer Inst. 2004 Sep 15;96(18):1402-3; author reply 1403-4. doi: 10.1093/jnci/djh280.
6
Re: Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instability.关于：遗传性非息肉病性结直肠癌（林奇综合征）及微卫星不稳定性的修订版贝塞斯达指南
J Natl Cancer Inst. 2005 Jun 15;97(12):936-7; author reply 937-8. doi: 10.1093/jnci/dji157.
7
Accuracy of revised Bethesda guidelines, microsatellite instability, and immunohistochemistry for the identification of patients with hereditary nonpolyposis colorectal cancer.修订的贝塞斯达指南、微卫星不稳定性及免疫组织化学在遗传性非息肉病性结直肠癌患者识别中的准确性
JAMA. 2005 Apr 27;293(16):1986-94. doi: 10.1001/jama.293.16.1986.
8
Frequent MSI mononucleotide markers for diagnosis of hereditary nonpolyposis colorectal cancer.用于遗传性非息肉病性结直肠癌诊断的常见微卫星单核苷酸标记物。
Asian Pac J Cancer Prev. 2010;11(4):1033-5.
9
Microsatellite instability of selective target genes in HNPCC-associated colon adenomas.HNPCC相关结肠腺瘤中选择性靶基因的微卫星不稳定性
Oncogene. 2005 Apr 7;24(15):2525-35. doi: 10.1038/sj.onc.1208456.
10
Genomic structure and alterations of homeobox gene CDX2 in colorectal carcinomas.结直肠癌中同源盒基因CDX2的基因组结构与改变
Br J Cancer. 1999 Feb;79(3-4):440-4. doi: 10.1038/sj.bjc.6690068.

引用本文的文献

1
Troponin T1 in tumorigenesis and immune modulation: Insights into multiple cancers and kidney renal clear cell carcinoma.肌钙蛋白 T1 在肿瘤发生和免疫调节中的作用：对多种癌症和肾透明细胞癌的深入了解。
J Cell Mol Med. 2024 Jun;28(11):e18410. doi: 10.1111/jcmm.18410.
2
The mechanism of mismatch repair and the functional analysis of mismatch repair defects in Lynch syndrome.错配修复机制及林奇综合征中错配修复缺陷的功能分析。
Fam Cancer. 2013 Jun;12(2):159-68. doi: 10.1007/s10689-013-9635-x.
3
Enhanced detection of microsatellite instability and mismatch repair gene expression in cutaneous squamous cell carcinomas.皮肤鳞状细胞癌中微卫星不稳定性和错配修复基因表达的增强检测
Mol Diagn Ther. 2006;10(5):327-34. doi: 10.1007/BF03256208.
4
Management of irritable bowel syndrome.肠易激综合征的管理
Postgrad Med J. 2003 Mar;79(929):154-8. doi: 10.1136/pmj.79.929.154.
5
CpG methylation of MGMT and hMLH1 promoter in hepatocellular carcinoma associated with hepatitis viral infection.与肝炎病毒感染相关的肝细胞癌中MGMT和hMLH1启动子的CpG甲基化
Br J Cancer. 2003 Feb 24;88(4):521-9. doi: 10.1038/sj.bjc.6600743.
6
Methods of molecular analysis: mutation detection in solid tumours.分子分析方法：实体瘤中的突变检测
Mol Pathol. 2002 Apr;55(2):73-9. doi: 10.1136/mp.55.2.73.

本文引用的文献

1
Hereditary colorectal cancer in the general population: from cancer registration to molecular diagnosis.普通人群中的遗传性结直肠癌：从癌症登记到分子诊断。
Gut. 1999 Jul;45(1):32-8. doi: 10.1136/gut.45.1.32.
2
DNA microsatellite instability in hyperplastic polyps, serrated adenomas, and mixed polyps: a mild mutator pathway for colorectal cancer?增生性息肉、锯齿状腺瘤及混合性息肉中的DNA微卫星不稳定性：结直肠癌的一种轻度突变途径？
J Clin Pathol. 1999 Jan;52(1):5-9. doi: 10.1136/jcp.52.1.5.
3
Microsatellite instability-a useful diagnostic tool to select patients at high risk for hereditary non-polyposis colorectal cancer: a study in different groups of patients with colorectal cancer.微卫星不稳定性——一种用于选择遗传性非息肉病性结直肠癌高危患者的有用诊断工具：一项针对不同组结直肠癌患者的研究
Gut. 1999 Jun;44(6):839-43. doi: 10.1136/gut.44.6.839.
4
The genomic challenge.基因组挑战。
BMJ. 1999 Feb 6;318(7180):341-2. doi: 10.1136/bmj.318.7180.341.
5
Selection, the mutation rate and cancer: ensuring that the tail does not wag the dog.选择、突变率与癌症：确保不要本末倒置。
Nat Med. 1999 Jan;5(1):11-2. doi: 10.1038/4687.
6
Frequency of replication errors in colorectal cancer and their association with family history.结直肠癌中复制错误的频率及其与家族史的关联。
Gut. 1998 Oct;43(4):553-7. doi: 10.1136/gut.43.4.553.
7
Genetic instability in colorectal cancer.结直肠癌中的基因不稳定
Gut. 1998 Oct;43(4):450-1. doi: 10.1136/gut.43.4.450.
8
Replication errors: cha(lle)nging the genome.复制错误：挑战基因组。 （注：原文中“cha(lle)nging”拼写有误，正确应为“challenging”）
EMBO J. 1998 Nov 16;17(22):6427-36. doi: 10.1093/emboj/17.22.6427.
9
Rapid and nonisotopic SSCP-based analysis of the BAT-26 mononucleotide repeat for identification of the replication error phenotype in human cancers.
Hum Mutat. 1998;12(5):355-60. doi: 10.1002/(SICI)1098-1004(1998)12:5<355::AID-HUMU9>3.0.CO;2-C.
10
The value of microsatellite instability in the detection of HNPCC families and of sporadic colorectal cancers with special biological features: an investigation on a series of 100 consecutive cases.微卫星不稳定性在检测遗传性非息肉病性结直肠癌（HNPCC）家系及具有特殊生物学特征的散发性结直肠癌中的价值：对连续100例病例的调查
Ann Oncol. 1998 Aug;9(8):901-6. doi: 10.1023/a:1008307611407.