Ikeya T, Ohwada S, Ogawa T, Tanahashi Y, Takeyoshi I, Koyama T, Morishita Y
Department of Surgery, Maebashi Red Cross Hospital, Gunma, Japan.
Hepatogastroenterology. 1999 Mar-Apr;46(26):959-66.
BACKGROUND/AIMS: The aim of this study was to identify factors that might affect the results of treating benign anastomotic stricture of the esophagus with balloon dilation.
Balloon dilation was performed on 35 patients with benign esophageal anastomotic stricture of the upper (esophageal cancer: 18) or lower (gastric cancer: 15, esophageal varices: 2) esophagus. The procedure was considered effective when patients were able to maintain a solid diet more than 12 months after the last dilation. The follow-up period ranged from 15-130 months (mean: 51 months).
A total of 245 dilations were performed, with an average of 6.6 dilations per patient. Treatment was effective in 29 patients (83%). Balloon dilation was successful when treating strictures shorter than 12 mm in length. The strictures were significantly shorter in patients treated effectively (5.6 vs. 30.8 mm). The diameter of the stricture did not affect the results. All the strictures in the lower esophagus and all those resulting from stapled anastomoses were treated successfully, while the effectiveness of treating strictures in the upper esophagus or those resulting from hand-sewn anastomoses was 67% and 57%, respectively. Strictures without prior leakage were treated effectively 92% of the time, while the success rate fell to 56% if there was a preceding leak. An average of 4.4 dilations were performed in effective cases, while the average was 17.5 dilations in ineffective cases. The number of repeat dilations was correlated with the length of the stricture.
Balloon dilation can successfully treat strictures shorter than 12 mm long. The correlation equation may be used to predict the number of repeat dilations and treatment results, and is useful for deciding when to use an alternative method to balloon dilation.
背景/目的:本研究旨在确定可能影响食管良性吻合口狭窄球囊扩张治疗效果的因素。
对35例食管良性吻合口狭窄患者进行球囊扩张,其中食管上段狭窄(食管癌:18例),食管下段狭窄(胃癌:15例,食管静脉曲张:2例)。当患者在最后一次扩张后12个月以上能够维持固体饮食时,该治疗方法被认为有效。随访期为15 - 130个月(平均:51个月)。
共进行了245次扩张,平均每位患者6.6次。29例患者(83%)治疗有效。治疗长度小于12mm的狭窄时球囊扩张成功。有效治疗的患者狭窄明显较短(5.6 vs. 30.8mm)。狭窄直径不影响治疗效果。食管下段的所有狭窄以及所有吻合器吻合所致的狭窄均治疗成功,而食管上段狭窄或手工缝合吻合所致狭窄的治疗有效率分别为67%和57%。既往无渗漏的狭窄92%治疗有效,而如果有先前渗漏,成功率降至56%。有效病例平均进行4.4次扩张,无效病例平均为17.5次扩张。重复扩张次数与狭窄长度相关。
球囊扩张可成功治疗长度小于12mm的狭窄。相关方程可用于预测重复扩张次数和治疗效果,有助于决定何时采用球囊扩张替代方法。