Hiramatsu K, Okamoto K, Uesaka K, Mukaiyama H, Seno T
Department of Surgery, Koseiren Kamo Hospital, Aichi, Japan.
Hepatogastroenterology. 1999 Mar-Apr;46(26):1160-3.
Fibrolamellar hepatocellular carcinoma (FLHCC), which is quite uncommon in Japan, is known to be frequently associated with lymph node metastasis in Western countries. Herein, we describe a case of a 25 year-old Japanese woman with recurrent FLHCC in the lymph nodes after undergoing right hepatic lobectomy. She underwent a second operation for removal of a recurrent celiac lymph node tumor 23 months after the initial operation. In Japan, the frequency of lymph node metastasis in ordinary hepatocellular carcinoma is only 1.6%, whereas 3 out of 9 (33%) reported domestic FLHCCs including this case had lymph node metastasis. The surgical management of lymph node metastasis in FLHCC is discussed.
纤维板层型肝细胞癌(FLHCC)在日本相当罕见,而在西方国家,它常与淋巴结转移相关。在此,我们描述了一例25岁的日本女性病例,该患者在接受右肝叶切除术后,淋巴结出现复发性FLHCC。初次手术后23个月,她接受了第二次手术,以切除复发性腹腔淋巴结肿瘤。在日本,普通肝细胞癌的淋巴结转移率仅为1.6%,而包括本病例在内的9例国内报道的FLHCC中,有3例(33%)发生了淋巴结转移。本文讨论了FLHCC淋巴结转移的外科治疗方法。